OIML G18 Controlled Vocabulary Julia Neumann 2022-12-16 2023-01-02 10:32:57 en-EN detection limit #01606 When applied in a measurement method or for an analysis, the limit of quantitation of the instrument is an important parameter. It is defined as being a value equal to 10 times the standard deviation of the background and also would include the variations associated with sampling and analysis concentration of an element which provides an output signalequivalent to three times the standard deviation of thebackground. It is the minimum quantity of an element that canbe detected. For this Recommendation, it may be derived fromthe statistical variation in the background using the followingequation:D = 3 (B/t)1/2/Swhere:D = detection limit (unit of concentration);B = background (counts per second);t = measurement time (seconds);S = sensitivity (counts per second per unit of concentration). 2022-12-19 13:03:54